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What is Dorsal Root Ganglion (DRG) Stimulation?

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March 20, 2024 Andrew Will

What is Dorsal Root Ganglion (DRG) Stimulation?

Dorsal Root Ganglion (DRG) stimulation is an advanced pain management therapy developed by Abbott. It is specially designed to provide relief from chronic neuropathic pain of the extremities.

Neuropathic pain results from damage to or malfunction of nerves. Nerves are the organs responsible for transmitting electrical and chemical signals all over the body. These signals are interpreted by the brain, and then the brain tells the body how to respond.

In the event that these nerves become aggravated, damaged, or begin to “malfunction, the body responds with the sensation of pain. If the nerves suffer severe trauma or are exposed to consistent aggravation, or stop working correctly, chronic neuropathic pain may develop. Chronic neuropathic pain can be challenging to treat because it is often difficult to pinpoint the location and source of nerve damage.

Learn more about neuropathic pain>>

What is the dorsal root ganglion?

The peripheral nervous system includes all the nerves that lead to and from the spinal cord. The dorsal root ganglion is a densely packed cluster of neurons that carry sensory signals from the peripheral nervous system to the central nervous system, which includes your spinal cord and brain.

The DRG are located near the dorsal root of a spinal nerve. Imagine the spine as a tree. If the nerves of the main spinal cord are the “trunk,” then the dorsal roots are where the “branches” begin.

Illustration highlighting the location of the dorsal root ganglion on the spineThe dorsal roots are the starting points for nerves that extend out to the furthest extremities. Since this is where the DRG are located, they receive sensory stimuli (such as pain) that originate in more distant parts of the body, such as the feet, legs, or arms.

What is Dorsal Root Ganglion (DRG) Stimulation?

DRG stimulation relieves extremity pain by applying electric pulses to the dorsal root ganglion. The DRG stimulator device consists of a pair of leads (thin, specialized wires) and a pulse generator (a kind of battery about the size of a silver dollar).

See-through image of a human body with a dorsal root ganglion (DRG) stimulator device implanted, along with a magnified view of the device lead resting next to a DRG in the spineA physician places the leads into the epidural space, where the DRG is. The battery is implanted in either the upper buttock or into the abdominal wall. The leads are then connected to the generator.

When the generator is turned on, it creates electric pulses which travel to the other ends of the leads which contain electrodes. The electrodes apply the electric pulses to the DRG. The electricity “stimulates” the nerves, blocking pain signals before they can reach the brain.

In the period after surgery, the leads can be programmed to give stimulation based on the pain pattern. Patients go home with a controller device that can alter stimulation settings.

Image of DRG system componentsDRG stimulation is similar to traditional spinal cord stimulation (SCS), with one very important difference. Rather than placing leads in a region of the spinal cord itself, DRG stimulation places the leads over the DRG. This targets the “branches” of the spinal cord that are receiving signals from the specific area causing pain, effectively shutting down that connection and relieving pain.

Dorsal Root Ganglion (DRG) Stimulation at Twin Cities Pain Clinic

Twin Cities Pain Clinic is one of Minnesota’s premier providers of DRG stimulation therapy. The list of physicians who are trained to perform the highly complex DRG stimulator implant procedure is short. Luckily, all four of our highly skilled physicians are among that select few.

If you are suffering from a chronic pain condition that affects the extremities, such as complex regional pain syndrome (CRPS) or peripheral neuropathy, schedule an appointment at Twin Cities Pain Clinic and see if DRG stimulation can provide you with the relief you deserve.

Resources

  1. Huygen, Frank J.P.M., et al. “Effectiveness and Safety of Dorsal Root Ganglion Stimulation for the Treatment of Chronic Pain: A Pooled Analysis.” Neuromodulation: Technology at the Neural Interface, vol. 23, no. 2, Feb. 2020, pp. 213–221, www.ncbi.nlm.nih.gov/pmc/articles/PMC7079258/, https://doi.org/10.1111/ner.13074.

Andrew Will

Dr. Andrew Will is a Physical Medicine & Rehabilitation physician specializing in pain management. He has been the Medical Director of Twin Cities Pain Clinic since 2003 and is one of the Midwest's foremost authorities in the diagnosis and treatment of acute and chronic pain. He has served as the President of the Minnesota Society of Interventional Pain Physicians and is a diplomate of both the American Board of Physical Medicine & Rehabilitation and the American Board of Interventional Pain Physicians.

Author Bio

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Andrew Will, MD
Founder & Medical Director
Twin Cities Pain Clinic
Dr. Andrew Will is a Physical Medicine & Rehabilitation physician specializing in pain management. He has been the Medical Director of Twin Cities Pain Clinic since 2003 and is one of the Midwest's foremost authorities in the diagnosis and treatment of acute and chronic pain. He has served as the President of the Minnesota Society of Interventional Pain Physicians and is a diplomate of both the American Board of Physical Medicine & Rehabilitation and the American Board of Interventional Pain Physicians.
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